6 Best Pet Safe Mice Poisons That Won’t Harm Your Furry Friends (Winter 2023)

An analysis of the best pet-safe mice poisons and their comparisons to target mice but not your pets.
By
Phyllis McMahon
Phyllis McMahon
Research Writer
Phyllis teaches English Literature at a local college and loves writing in her free time. She’s also a great cook – her British beef Wellington is something the best res read more
reviewed
Reviewed By
Chas Kempf
Chas Kempf
Expert Consultant
Chas works in a professional pest control company and knows all the nuances of this job. Also, he’s a fantastic tennis player and loves to organize BBQ parties for his fam read more
Last updated: December 17, 2022
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Vomiting, diarrhea, seizures, internal bleeding, and even death are potential consequences that you can face if your pet consumes a mice poison (God Forbid!). Fortunately, there is a way to knock off mice without hurting your pets by using pet-safe mice poison.

We’ve tested 16 products and compiled a list of the 6 best pet-safe mice poisons. The MouseX All-Natural Non-Toxic Mouse Killer is our favorite. On the list, you’ll find products with such active ingredients as corn gluten meal and sodium chloride which target the gastrointestinal tract of a mouse but don’t influence pets because their bodies work differently.

Quick Summary

Top 6 Pet Safe Mice Poisons Review 2023

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Features
  • Form: pellets
  • Active ingredients: corn gluten meal, sodium chloride
  • For use: indoors and outdoors
  • Effect: in 3-5 days
  • Target species: mice

The MouseX Mouse Killer is our Editor’s Choice on the list of the best pet-safe mice poisons because it contains corn gluten meal and sodium chloride, derived from all-natural ingredients, making these pellets deadly for mice and absolutely safe for humans and pets, livestock, and wildlife. These pellets can be used both indoors and outdoors, so it’s also a versatile product. It takes 3 to 5 days to kill a mouse with these pellets. This poison also reduces 95% of the odor of dead mice, as this product dehydrates them from the inside.

With the MouseX All-Natural mouse killer, you get the same active ingredients as you would with the RatX Bait Discs. These include corn gluten meal and sodium chloride. However, the method for administering them is different, with one being pellets while the other is discs. Of course, it comes down to preference and where you intend to deploy the poison. We noticed that if you’re deploying in tighter spaces, the pellets of the MouseX may be better.

    What makes it special?
  • Contains no chemicals so non-toxic for all living species except for mice, rats, and voles;
  • Contains food-grade ingredients so it is eco-friendly;
  • It is easy to use, just put it in a place with the most mouse activity;
  • Starts working after the first feeding.
    What cons did we find?
  • Multiple applications are needed.
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9.2
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2
Easiest-to-Apply

MouseX Throw Packs

Features
  • Form: pellets
  • Active ingredients: corn gluten meal, sodium chloride
  • For use: indoors and outdoors
  • Effect: 3-5 days
  • Target species: rats and mice

When you are facing mice infestation, there’s little time for hesitation. However, the MouseX Throw Packs will help you in your fight against them. The MouseX Throw Packs are really easy-to-use, you don’t even need to open them, just throw them as they are and they’ll work. This product is a naturally derived rodenticide that comes in a form of pellets that are palatable by mice and rats. There is no risk of secondary poisoning with the MouseX Throw Packs pellets. It is also a biodegradable product, so you won’t pollute the environment when using it outside. Plus, this product doesn’t need any special requirements for transporting and storage.

When comparing the MouseX Throw Packs and MouseX pellets, we noticed that these two have the same active ingredient (corn gluten meal) and they both come in a form of pellets. These are also the easiest to set up products as they don’t require much time for it. Nevertheless, if you need bait trays, the ones provided with the MouseX pellets should work fine. The MouseX Throw Packs alternative is a better pick if you just want to place the bait and forget about it for a while.

    What are our favorite features?
  • Easy application as no mixing and additional actions are required;
  • No chemicals are used in it so your loved ones are protected;
  • It also prevents re-infestation as mice and rats will be scared to eat them.
    What could be better?
  • It is pricey.
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3
Best for Outdoor Use

RatX Bait Discs

Features
  • Form: discs
  • Active ingredients: corn gluten meal, sodium chloride
  • For use: indoors and especially outdoors
  • Effect: n/s
  • Target species: rats and mice

For outdoor use, you need a product that is specifically designed for it like the RatX Bait Discs. They are weather-resistant and are supposed to be used in an outdoor bait box so no weather conditions will stop you from eradicating these pesky pests. When using these discs, you don’t need to worry about your pets and kids, as this product is also made of natural products and won’t harm them in any way. Also, it won’t contaminate your crops or food so rest assured about this.

What differentiates the RatX Bait Discs from the other RatX product, which is the All-Natural Non-Toxic Rat and Mouse Rodenticide Pellets, is the distribution form. The discs are much wider and bigger and should be easier for mice to locate outdoors. However, if the mice are hiding in walls and cracks in your house, we believe the pellets are much more likely to reach them.

    What are our favorite features?
  • Weatherproof so can be used in humid conditions;
  • They work against any type of mice – from house to field;
  • They are simple in usage;
  • No chemicals are used so no worries about poisoning or contaminating your food.
    What could be better?
  • Quite expensive compared to other products on the market.
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Features
  • Form: concentrate
  • Active ingredients: peppermint oil
  • For use: indoors and especially outdoors
  • Effect: in 1-2 days
  • Target species: mice and rats

Our next product for review is not a poison but instead a repellent which is actually the Best Humane Option as it won’t kill even mice and rats and, of course, won’t harm you or your pets. It is a spray concentrate with pure peppermint oil that is supposed to be mixed with water before applying. As it is made with essential oil, it has a pleasant smell to humans and won’t bother you at all but it will irritate mice and other rodents. It can be used both inside and outside, just add 16 ounces of water to every ounce of concentrate to get a ready-to-use spray.

Compared to all products on the list, this one stands out the most. First, it’s a repellent and not a poison or killer, in spite of that it works amazingly with no harm at all so it’s also the most humane option. Secondly, it’s the only concentrate option, so if you don’t want to mess with mixing, opt for the others. Thirdly, you’ll need some additional equipment for spreading this spray around, so prepare yourself in advance.

    What do we love it for?
  • Doesn’t kill mice but only repels them;
  • Made of natural ingredients;
  • Has a pleasant smell thanks to peppermint oil;
  • Strength formula for long-lasting results.
    What were we disappointed with?
  • A spray bottle and a nozzle are not included so additional equipment is needed.
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Features
  • Form: pellets
  • Active ingredients: corn gluten meal, sodium chloride
  • For use: indoors and especially outdoors
  • Effect: in 1-2 days
  • Target species: mice and rats

Sometimes you don’t know how and where to place the bait, that’s where the MouseX All pellets come in. This product comes with bait trays filled with the bait, all you have to do is to open it and place where you’ve seen mice. Coming in a form of pellets and containing all-natural ingredients, this product is perfect for targeting mice and rats, and leaving all other living beings safe. It is also convenient to take with you anywhere you go like a campsite because it comes in a small package. Plus, there are no storage or transportation restrictions. However, take note that this product is ineffective against voles, gophers, and moles.

There are some similarities between the MouseX pellets and the RatX Bait Discs. Even though these two come in different forms (pellets and discs), they still have a lot in common. They are made of the same ingredient and can be used outdoors. The RatX can be used in such conditions as it’s weather-resistant and best used in outdoor bait stations, while the MouseX pellets come with 4 trays that will also protect poison from harsh weather.

    Why are we impressed?
  • Comes with 4 bait trays;
  • Can be taken with you at any place;
  • Made of food-grade components which are safe for everyone except mice and rats;
  • No suffering for mice as it acts fast and humanely;
  • Can be used indoors and outdoors.
    What negatives must you be aware of?
  • Not that effective in winter;
  • The package can come damaged but it won’t influence the quality of the pellets.
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6
Most Versatile

Kaput Rat Mouse Vole Bait

Features
  • Form: grain granules
  • Active ingredients: 0.25% Warfarin
  • For use: indoors and especially outdoors
  • Effect: in 10 days
  • Target species: rats, mice, voles

One of the most versatile products is the Kaput Rat Mouse Vole Bait. As the name implies, it can help you in getting rid of rats, mice, and moles. This product contains 0.25% Warfarin which is effective in mouse, rat, and vole eradication but poses no or low threat to other animals. Also, if it is used as directed (put into a bait station), your pets will be 100% protected from secondary poisoning. In all states, it is recognized as a rodenticide bait and as the safest chemical option for rodent control. Rodents will swallow this rodenticide easily, as the product imitates grain.

Compared to the rest of the list, this is the only option to come in a 4 lb package which, in our opinion, makes it ideal for a large infestation. The other difference is in the active ingredients used with this option having warfarin, while the other products have naturally-derived ingredients. Lastly, all the poisons given above are effective against mice. However, if you have more than that to deal with, i.e., voles, this option should be a better pick.

    Why did it make our list?
  • It is versatile and targets mice, rats, and voles at the same time;
  • Safe to use around pets and children when used as directed;
  • Low chances of secondary poisoning;
  • It mimics grain being an attractant for rodents.
    What is not ideal about it?
  • A bait station is needed;
  • Not as safe as the ones with natural ingredients.

Things to Consider

When you are an owner of a furry friend, you choose mice poisons with caution as you don’t want to put your pet in danger. However, mice cause some major troubles and that’s why we’ve prepared some tips on how to choose an effective mice poison without harming your pet. We’ll look at the level of toxicity of poisons, what active ingredients they contain, the effectiveness of a bait indoors and outdoors and some storage tips so that your pet won’t have an access to it.

Safety Precautions

If you decide to use poisons for eradicating mice, keep in mind that there is still some risk if your pet swallows even a tiny piece of bait. It is due to the fact that baits are also flavored to make them more attractive to mice and rats. Your pets can walk into this ‘trap’ too. Especially when EPA says that at least a hundred pets die each year from poisoning with rodent baits.

How to Reduce the Risk of Poisoning Your Pet

6 Best Pet Safe Mice Poisons That Won't Harm Your Furry Friends (Winter 2023)
It doesn’t matter what poison you choose, there are still some rules to follow to prevent your pet from poisoning.

As we always say, read the label and instructions from the manufacturer first. However, while researching, we’ve compiled a list of our own rules:

  1. Storage. Pay attention to how you leave the package. Make sure it is always sealed. It’s better to keep it out of kids’ and animals’ reach. High shelves in a locked cabinet seem like a safe place.
  2. Bait stations. Place mice poison in a bait station. Your pets and kids won’t manage to open them. Plus, many of them are weather-resistant so can be used both indoors and outdoors.
  3. Don’t Mix It with Pet Food. Never mix mice poison with peanut butter, pet food, meat paste, or any other food. Mice poisons are already created to be attractive to rodents, there’s no need to make it more appealing, especially for your pets.
  4. Constant monitoring. Try to check the baits as often as possible and also inspect your house for dead mice. If you see one, immediately remove them. It’s worth putting them in a high bin. This way you lower the chances of secondary poisoning.
  5. Talk to family. Let all your family members know that you set out some mice and rat poisons around your house and tell them about the risk of poisoning your furry friends.
  6. Talk to your neighbors. In some cases, you might do everything right but your neighbors might not know about these rules. Ask them whether they use rodenticides or not. If they do, ask them to put it in station baits.
  7. Install a fence. If it turns out that your neighbors care only about themselves and won’t make concessions with bait stations. Think of installing the fence, so that your pets won’t find a way to your neighbors’ baits.

Disadvantages of Pet-Safe Poisons

  • Low efficiency. Most pet-safe poisons will be made of natural ingredients or chemical ones but at a low dosage so the efficiency of the product will be lowered. Several feeding can be needed for mice to die. Plus, mice can evolve and get used to some of the chemical poisons with Warfarin.
  • Quantity. Always remember to follow the manufacturer’s instructions. If it’s said to put a teaspoon of bait, do it. Most mice poisons are pet-safe only in small amounts. Forgetting that quantity makes up for potency, you may put your pet in even more danger.
  • A false feeling of safety. When buying a poison with the label ‘pet-safe’, do not relax that fast. Poison is still a weapon in your hands that poses threat to your pet’s health and life. Stay cautious even if it’s pet-safe, read the label attentively and use or tips we give you.

How to Choose the Best Pet-Safe Poisons

Here we’ll discuss some features to look for in pet-friendly mice poisons like active ingredients, form, effectiveness, and target species.

Active Ingredients

Mice poisons that are safe for pets usually have quite a small list of ingredients. There exist two main mice poisons:

  • Natural mice poison: These usually contain some food-grade components like corn gluten meal and Sodium Chloride. This type of poison will affect only mice, rats, and voles as they have a unique digestive system, different from other animals and humans. When corn gluten meal is swallowed, it affects the stomach and intestine of a rodent, so these organs become unable to signal to the brain that the rat or mouse is thirsty. In conjunction with sodium chloride which is a dehydrating agent, this type of product dehydrates the rodent until it falls asleep and dies.
  • Chemical mice poison: Some chemical mice poisons can be used by pet owners. These often contain a low dosage of Warfarin, Bromadiolone, and Diphacinone that according to manufacturers shouldn’t affect your pet. These ingredients inhibit Vitamin K and prevent blood from clotting, so the rodent will die from internal bleeding.

However, when applying a chemical rodenticide like this, make sure you read the instructions on the label carefully. As these often say that you need to use the chemical bait only in a bait station. Then you’ll make it impossible for your pet to access bait or a poisoned mouse.

Form

Consider the form of this or that product you want to buy. As it should be palatable for mice and even mimic their favorite food. We advise looking for poison baits that are smaller in size, like pellets, and grains. However, discs can also work if used properly. Bigger-sized poison baits like chunks might require additional actions from you. You may need to break them into pieces or chop them down.

Effectiveness

Always bear in mind that pet-safe rodenticides work more slowly than the ones without such a label. So when applying these products, don’t wait for instant results. Give mice some time to consume the dosage; several feedings are often required. We’d recommend checking the baits and bait stations for at least 3 days. If you have a large mouse infestation, it can take more time to eradicate the scope. Two weeks are already an indicator of whether the poison works or not.

Target Species

Always check what species the poison targets. Usually, manufacturers place it on the label or their website. Mostly, mice poisons kill other rodents like rats and voles, making them also versatile options.

Rodenticides to Avoid

As we’ve already mentioned chemical rodenticides are the most dangerous for your pets. They can cause internal bleeding, kidney failure, and even destroy the cellular metabolism of the body. Each poison has its effect. A lot depends on the level of toxicity (probability of recovery and antidote requirement).

If your pet got poisoned from one of these, make sure to give it to the vet, for a speedy solution to the problem.

There are three main categories of rodenticides

Highly toxic

  • Aluminum phosphide
  • Arsenic
  • Barium carbonate
  • Bromethalin – dose dependant and no antidote (treatment)
  • Elemental phosphorus
  • Sodium monofluoracetat
  • Strychnine
  • Thallium
  • Zinc phosphide

Moderately Toxic

  • Alpa-naphthyl thiourea (ANTU)
  • Cholecalciferol
  • Diaphacinone
  • Dipazin
  • Diphenacin

Toxic

  • Brodifacoum
  • Bromodialone
  • Chlorophacinone
  • Difenacoum
  • Difethialone
  • Norbormide
  • Red squill
  • Superwarfarin
  • Warfarin

Signs of Your Pet Poisoning

6 Best Pet Safe Mice Poisons That Won't Harm Your Furry Friends (Winter 2023)
It takes around three to four days for symptoms of poisoning to show up.

At times, symptoms show up right away, while others can take months to bring visible damage to your pet’s health.

Although we don’t recommend that you wait till the signs of poisoning in your pet. Here are some of the most common:

  • Lethargy
  • Pale gums
  • Trouble breathing/increased breathing rate
  • Weakness/collapse
  • Vomiting
  • Tremor/seizures
  • Decreased appetite
  • Stomach bloating/abdominal pain
  • Increased thirst and increased urination

Actions to Take When Your Pet Consumed Mice Poison

If you detected one of the signs listed above, don’t panic. As every minute counts, you don’t want to waste it irrationally.

First, call your vet immediately or call one of these animal poison control centers based in North America:

Pet Poison Helpline: 1-855-764-7661

ASPCA Animal Poison Control Center: 1-888-426-4435


If you’re worried about your pet, the best thing to do is speak with a veterinary professional as soon as possible. They can help you take the appropriate steps to care for your pet and avoid any potential problems.

Also, find the package of the mice poison you used. You’ll need to provide the information from it (EPA registration number, active ingredients, and concentration).

Other Pet-Safe Ways to Eliminate Mice

Poison is not the only solution for mice elimination. These won’t harm your pet and some of them are even humane to mice.

  • Humane mouse traps are the first that come to our minds. There are humane traps that capture a mouse alive and afterward you can release it somewhere away from your house. Just make sure you’re wearing gloves while setting the trap and releasing a mouse. These traps also won’t harm your pet. If you want to choose this most humane way of mouse eradication, then it’s worth checking our compilation of the best humane mouse traps.
  • Electronic mouse traps. You can find this type of trapping a bit inhumane but it works well against them only. These traps have a special sensor that senses when a mouse enters the trap, then it triggers a high-voltage shock and kills a mouse fast and with no torment. In some senses, it’s more humane than a snap trap. If you want to try out this method to eradicate mice in your house, you should read our analysis of the best electronic mouse traps.
  • Mouse repellents. To keep mice at bay, you can also use repellents. They usually include some natural oils like peppermint, garlic, or cayenne pepper. These ingredients will repel mice from your property triggering their sense of smell. However, it isn’t supposed to harm them. There are also ultrasonic mouse repellents that emit high-frequency sound with no harm to humans and pets. Some of these can be solar-powered, and others must be plugged in. So you have a wide variety of options to use them either indoors or outdoors. For a more detailed guide and product reviews, check out the best mouse repellents.

Mice Infestation Prevention Tips

  • Seal holes and cracks. Rodents are sneaky animals that will find the tiniest hole or crack in your house. Your task is to get ahead of mice and rats. Find small holes and fill them with steel wool. Then add caulk around the steel wool to keep it in place. For larger holes and cracks use anything like a lath screen or lath metal, cement, hardware cloth, or metal sheeting.
  • Store food in containers. Store all your food in glass or plastic containers with hard sides that are tightly closed. Avoid leaving these containers on the floor or in lower cabinets.
  • Keep everything clean. On a regular basis, carry out cleaning and revision both inside and outside. This includes your yard, trash cans, pet and bird feeders, cupboards, etc.

FAQ

Do DIY poisons work against mice and don’t harm my pet?

Certainly, some of them do work, these include baking soda, aspartame, cement mix, Vitamin D3, and even mashed potato flakes. However, not all of them are safe to use around kids and pets. So before using one of these, it’s better to consult with your vet.

The answer is no. It is a common stereotype that milk can help a poisoned dog. In reality, it has nothing to do with first aid for a poisoned dog. In turn, it can even worsen the situation as some of the dogs are lactose intolerant and it can lead to stomach upset symptoms.

How long does it take for the pet-safe poison to kill a mouse?

It actually depends on active ingredients and the amount digested. Pet-safe options will take longer to work – from 3 to 5 days of regular feeding. However, for more impressive results, wait at least 2 weeks.

Will mice leave if you have a cat?

While the smell of your cat (the predator) scares the mice away, it doesn’t mean the mice have left your home. Cats are not as tiny as mice and therefore they can’t get through holes and cracks and approach such areas as walls and crawlspaces. But mice will learn this quickly and use these spaces to hide.

Our verdict

Our 1st place took the MouseX Mouse Killer which is our Editor’s Choice. It’s an extremely effective poison made of natural ingredients, which won’t harm any living beings except rodents.

Next on the list, you’ll find a product that is the Easiest to Apply. The MouseX Throw Packs are supposed to be just put in areas of the most mice activity without any need to open them or mix them with water.

Lastly, there’re the RatX Bait Discs, which are Best for Outdoor Use as they are weather-resistant and perfect for use in outdoor bait boxes thanks to their disc form.

Hope you’ll find your perfect option in our review of the best pet-safe mice poisons.

References

1.
Is There a Mouse in the House? Eliminate Mice with IPM
Explains how to identify, prevent, and control mice using IPM integrated pest management.
2.
Control of Mice Entomology
The house mouse is remarkably well-adapted for living year-round in homes, food establishments and other structures. Homeowners are especially likely to notice mice during winter, following their fall migration indoors in search of warmth, food and shelter. Once mice become established inside a home, they can be extremely difficult to control.
9,8
Total Score
MouseX All-Natural Non-Toxic Mouse Killer - Editor's Choice
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